Tretinoin dangers? VA study explained 🤔 Dermatologist @Dr Dray
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Tretinoin dangers? VA study explained 🤔 Dermatologist @Dr Dray


Tretinoin dangers? VA study explained 🤔 Dermatologist @Dr Dray on the safety of tretinoin for long term use. Increased deaths observed in VA study of tretinoin 0.1 cream. Is Retin A safe? Retin A dangers, death and lung cancer risk debunked. #tretinoin #antiagingskincare #dermatologist
10 reasons you tretinoin isn’t working https://youtu.be/nxxQoBuvkvw
5 myths about tretinoin https://youtu.be/2p1CNeQgffc

References
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Chemoprevention (VATTC) Trial Group. Topical tretinoin therapy and all-cause mortality. Arch Dermatol. 2009;145(1):18-24.
Katz KA. Topical tretinoin, lung cancer, and lung-related mortality. Arch Dermatol. 2008;144(7):945-946.
The Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group. The
effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. N Engl J Med. 1994;330(15):1029-1035.
Omenn GS, Goodman GE, Thornquist MD, et al. Effects of a combination
of beta carotene and vitamin A on lung cancer and cardiovascular disease. N Engl J Med. 1996;334(18):1150-1155
Wang XD, Liu C, Bronson RT, Smith DE, Krinsky NI, Russell M. Retinoid signaling and activator protein-1 expression in ferrets given beta-carotene supplements and exposed to tobacco smoke. J Natl Cancer Inst. 1999;91(1):60-66.
Rigas JR, Miller VA, Zhang ZF, et al. Metabolic phenotypes of retinoic acid
and the risk of lung cancer. Cancer Res. 1996;56(12):2692-2696.
Rosenberg EW, Skinner RB Jr. Topical retinoids: another piece for the retinoid cigarette-lung cancer puzzle? J Thorac Oncol. 2006;1(7):732.
Liddell FDK. The interaction of asbestos and smoking in lung cancer. Ann Occup Hyg. 2001;45(5):341-356.
Latriano L, Tzimas G, Wong F, Wills RJ. The percutaneous absorption of topically applied tretinoin and its effect on endogenous concentrations of tretinoin and its metabolites after single doses or long-term use. J Am Acad Dermatol. 1997 Mar;36(3 Pt 2):S37-46.

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